CPSR

From £70 · 2 to 3 days

The Cosmetic Product Safety Report is the safety assessment required under Article 10 and Annex I of Regulation (EC) No 1223/2009 before a cosmetic product may be placed on the UK or EU market. Prepared and signed by a qualified safety assessor.

FDA MoCRA

US market entry under MoCRA: a MoCRA-compliant Toxicological Risk Assessment with the state-level provisions for California, Washington, New York and Minnesota, prepared by the same assessor who signs our EU and UK CPSRs.

Global Markets

Cosmetic regulatory documentation for markets beyond the EU and UK: Canada, Australia, New Zealand, ASEAN, the GCC and Latin America, prepared from the same evidence base by the assessor who signs our CPSRs.

Labelling

from receipt of artwork

Independent review of packaging artwork against Article 19, and of product claims against the six Common Criteria of Regulation (EU) 655/2013, as fixed-fee engagements.

Regulatory Watch

Alert within 5 working days of publication; no digest is sent in weeks with no hit

Cosmetic Regulatory Watch checks every change to cosmetic ingredient law in each market you sell in against your actual formulation, and tells you when the law changes and your CPSR needs to. Per product per year, quoted on request.

Responsible Person

per product, per year

Oxford Biosciences acts as your Responsible Person in the UK and the EU under a single quality management system, holding the regulatory obligation: PIF maintenance, SCPN and CPNP notification, labelling oversight, and cosmetovigilance.

Testing

Stability, microbiology, photoprotection and analytical testing carried out in our three in-house laboratories. Analytical work is not contracted out; results pass directly to the assessor preparing your CPSR.

Cosmetovigilance

Receipt, assessment and reporting of undesirable and serious undesirable effects under Article 23, with direct interface to the competent authority on the brand's behalf.

Border Detention

Expedited

Rapid resolution where a cosmetic shipment is detained at a port of entry for missing or deficient compliance documentation.

Claims Testing

From £5,000 · 3 to 5 months

Clinical efficacy studies that generate the measured evidence a cosmetic claim needs, to a standard a regulator or a broadcaster will accept. For anti-ageing, brightening and other performance claims.

Crisis Management

A single point of regulatory control when an incident, an enforcement action or an adverse finding threatens a product or a brand.

Dermatological Testing

ROAT: 5-day application phase, report within 3 weeks of study start. HRIPT: 6 to 7 weeks of study, report typically 8 to 10 weeks from study start

Human skin compatibility studies for cosmetic products under the supervision of a Clinical Pharmacologist. Repeated Open Application Test (ROAT) for irritation and Human Repeat Insult Patch Test (HRIPT) for sensitisation, conducted to the Declaration of Helsinki, ICH E6(R2) and the COLIPA skin compatibility guidelines, and reported for the CPSR and for dermatologically tested and hypoallergenic claims.

DPPH

5 working days from receipt of sample

Quantitative antioxidant capacity of cosmetic products, extracts and raw materials by the DPPH radical scavenging assay. UV-Vis spectrophotometry at 517 nm, calibrated against Trolox and ascorbic acid, results as percentage inhibition, IC50 and Trolox equivalents, conducted in our own laboratory and reported for claims substantiation and the Product Information File.

Essential Oils GC/MS

3 to 5 weeks from receipt of sample

Full constituent listing of essential oils, hydrolats, absolutes and perfume compounds by gas chromatography-mass spectrometry, with quantification of the Annex III fragrance allergens, restricted constituents such as methyl eugenol, estragole and furocoumarins, and adulteration checks. Reported for the CPSR and for allergen labelling under Regulation (EU) 2023/1545.

Formaldehyde Testing

5 working days from receipt of sample

Determination of free and released formaldehyde in cosmetic products by HPLC-UV after DNPH derivatisation, with results assessed against the 0.001 percent (10 ppm) 'releases formaldehyde' labelling threshold introduced in the EU by Regulation (EU) 2022/1181, the 0.05 percent threshold retained in Great Britain, and the prohibition of formaldehyde itself under Annex II.

Heavy Metals Testing

5 working days from receipt of sample

Quantification of lead, arsenic, cadmium, mercury, antimony, nickel, chromium and cobalt in cosmetic products and raw materials by inductively coupled plasma mass spectrometry, with results assessed against Annex II of Regulation (EC) No 1223/2009, the Article 17 technically unavoidable trace provision, and the trace limits applied in the EU, UK, Canada, USA, ASEAN and China.

MSDS

Preparation of a Material Safety Data Sheet for a finished cosmetic product or an individual ingredient, in line with the applicable Annex II provisions of REACH and the Globally Harmonised System.

Notifications

Notification of cosmetic products to the EU Cosmetic Products Notification Portal and the Great Britain Submit Cosmetic Product Notifications service, with amendments and withdrawals managed within the regulated timeframes.

PET / Challenge Test

28-day test plus neutraliser validation; report typically 5 to 6 weeks from receipt of sample

Preservative Efficacy Testing to ISO 11930:2019 for cosmetic products. Five reference organisms, neutraliser validation, 28-day log reduction against Criteria A and B, and a report written for the CPSR. Conducted in our own microbiology laboratory.

PFAS Testing

Formulation review within 5 working days; analytical results typically 3 to 4 weeks from receipt of sample

Screening and quantification of per- and polyfluoroalkyl substances in cosmetic products and raw materials: formulation review for fluorinated ingredients, total organic fluorine screening by combustion ion chromatography, and targeted LC-MS/MS for PFHxA, PFOA, PFOS and related compounds against the 25 ppb and 1,000 ppb limits of REACH Annex XVII entry 79 applicable to cosmetics in the EU from 10 October 2026, the POPs Regulation, and the US state prohibitions on intentionally added PFAS.

PIF Compilation

Compilation of the Article 11 Product Information File: the dossier a Responsible Person must hold for every cosmetic and produce to a competent authority on request.

Rapid Response

24 to 48 hours

Expedited regulatory support when a deadline, a detained shipment or an incident cannot wait for standard turnaround.

Recall Management

Support in managing a cosmetic product recall or withdrawal, from assessing the safety issue through authority notification to a documented corrective action plan.

Stability Testing

12-week accelerated programme as standard; interim reports at 4 and 8 weeks on request; real-time studies to 12, 24 or 36 months

Accelerated and real-time stability testing of cosmetic products to the Cosmetics Europe Guidelines on Stability Testing. Quantitative pH, viscosity, density and organoleptic data, freeze-thaw and light exposure, centrifugation, and packaging compatibility, reported for the CPSR and the period-after-opening decision.